Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, maximum
Lease Expiration Date
Operating lease expiration date
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period
Vesting period
Contingent Consideration by Type [Axis]
Contingent Consideration by Type
Change in Accounting Principle, Accounting Standards Update, Early Adoption [true false]
Change in accounting principle, accounting standards update, early adoption
Certificates of Deposit [Member]
Certificates of Deposit
Operating Loss Carryforwards
Net operating loss carryforwards
Operating Loss Carryforwards, Total
Temporary Equity, Shares Authorized
Convertible preferred stock, authorized
Shares Authorized
Temporary equity conversion to common stock shares.
Temporary Equity Conversion To Common Stock Shares
Conversion to Common Stock (in shares)
Auditor Location
Other Comprehensive Income (Loss), Net of Tax
Other comprehensive loss
Other Comprehensive Income (Loss), Net of Tax, Total
Operating Expenses [Abstract]
Operating expenses:
Operating Income (Loss)
Loss from operations
Operating Income (Loss), Total
Success based milestones.
Success Based Milestones [Member]
Success Based Milestones
Weighted Average Number of Shares Outstanding Reconciliation [Abstract]
Denominator
Entity Emerging Growth Company
Entity Emerging Growth Company
Investment, Policy [Policy Text Block]
Investments
Income Tax Disclosure [Abstract]
Financial Instrument [Axis]
Financial Instrument
Prepaid expenses and other assets
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
South San Francisco and San Diego locations.
South San Francisco And San Diego Locations [Member]
South San Francisco and San Diego Locations
Schedule of Cash, Cash Equivalents and Restricted Cash
Schedule of Cash and Cash Equivalents [Table Text Block]
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant
Number of common stock remained available for issuance
Payments to Acquire Property, Plant, and Equipment
Acquisitions of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Noncash or Part Noncash Acquisition, Fixed Assets Acquired
Amounts accrued for purchase of property and equipment
Geographical [Axis]
Geographical
Common stock, $0.0001 par value; 1,000,000,000 shares authorized; 39,430,120 and 36,672,415 shares issued and outstanding at December 31, 2021 and 2020, respectively
Common Stock, Value, Issued
Upfront payment value
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Entity Address, State or Province
Entity Address, State or Province
Liabilities
Total liabilities
Mirati Therapeutics, Inc.
Mirati Therapeutics Inc [Member]
Mirati Therapeutics, Inc
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
License fees.
License Fees Policy [Text Block]
License Fees
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Stockholders' Equity, Reverse Stock Split
Reverse stock split
Income tax.
Income Tax [Table]
Income Tax [Table]
Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]
Summary of Future Minimum Lease Payments under Non-cancelable Operating Leases
License agreements.
License Agreements [Line Items]
License Agreements [Line Items]
Class of Stock [Domain]
Class of Stock
Convertible Preferred Stock, Shares Issued upon Conversion
Outstanding shares of convertible preferred stock converted into shares of common stock
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Unrealized loss on available-for-sale securities
Weighted Average Number of Shares Outstanding, Basic and Diluted
Weighted-average shares outstanding, basic and diluted
Weighted average shares outstanding used in computing net loss per share, basic and diluted
Defined Contribution Plan, Employer Discretionary Contribution Amount
Employer contribution amount
General and Administrative Expense [Member]
General and administrative
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term (in years), Exercisable
Series B Preferred Stock [Member]
Series B Convertible Preferred Stock
Debt Securities, Available-for-sale, Current, Total
Debt Securities, Available-for-sale, Current
Short-term investments, available-for-sale
City Area Code
City Area Code
Proceeds from Sale of Notes Receivable
Proceeds from notes receivable
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Summary of Fair Value of Stock Options Estimated Using Black-Scholes Merton Option Pricing Model Assumptions
Deferred Tax Assets, Gross
Gross deferred tax assets
Temporary Equity, Par or Stated Value Per Share
Convertible preferred stock, par value
Deferred Tax Assets, Net of Valuation Allowance
Total deferred tax assets
US Treasury Securities [Member]
U.S. Treasury Securities
Two thousand twenty equity incentive plan.
Two Thousand Twenty Equity Incentive Plan [Member]
2020 Plan
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in accounting principle, accounting standards update, adopted
Commitments and Contingencies
Commitments and contingencies (Note 11)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Summary of Outstanding Shares of Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
Research and development credit
Stock Issued During Period, Shares, New Issues
Offering of common stock (in shares)
Shares of common stock issued
Debt Securities, Available-for-sale
Estimated Fair Value
Available for sale, Investment
Debt Securities, Available-for-sale, Total
Scenario [Axis]
Scenario
Accrued Salaries, Current
Accrued compensation
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Number of shares issued under ESPP
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents
Cash and cash equivalents, end of period
Cash and cash equivalents, beginning of period
Total cash, cash equivalents and restricted cash presented in the statement of cash flows
Share based compensation arrangement by share based payment award stock options not be granted at less than fair market value of common stock at date of grant percentage.
Share Based Compensation Arrangement By Share Based Payment Award Options Not Be Granted At Less Than Fair Market Value Of Common Stock At Date Of Grant Percentage
Percentage of options may not be granted at less than fair market value of the common stock at the date of grant
Liquid investments maturity period.
Liquid Investments Maturity Period
Liquid investments maturity period
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change in accounting principle, accounting standards update, early adoption
Stock Issued During Period, Value, Conversion of Convertible Securities
Conversion to Common Stock
Income Statement [Abstract]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Other Nonoperating Income (Expense) [Abstract]
Other income:
Income tax.
Income Tax [Line Items]
Income Tax [Line Items]
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Tax Credit Carryforward [Axis]
Temporary Equity [Abstract]
Convertible preferred stock:
Share-based Compensation Arrangement by Share-based Payment Award, Percentage of Outstanding Stock Maximum
Percentage of outstanding shares of common stock
Tax Credit Carryforward, Name [Domain]
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
Property, Plant and Equipment, Net
Property and equipment, net
Total property and equipment, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Common Stock, Shares, Issued
Common stock, shares, issued
Upfront payment shares issued
Common Stock, Shares, Issued, Total
Debt Securities, Available-for-sale, Amortized Cost
Amortized Cost
Amortized Cost
Operating Lease, Right-of-Use Asset
Operating Lease, Right-of-Use Asset
Right-of-use assets
Security Exchange Name
Security Exchange Name
Statistical Measurement [Domain]
Statistical Measurement
Furniture and Fixtures [Member]
Furniture and Fixtures
Property Plant and Equipment Impairment Loss
Property Plant And Equipment Impairment Loss
Impairment of property and equipment
License agreements.
License Agreements [Abstract]
License agreement cash payment related to acquired assets charge.
License Agreement Cash Payment Related To Acquired Assets Charge
License agreement cash payment related to acquired assets charge
Other Liabilities, Noncurrent, Total
Other Liabilities, Noncurrent
Other long-term liabilities
Fair value, assets, level 1 to level 3 transfers, amount.
Fair Value Assets Level1 To Level3 Transfers Amount
Transfer between level 1 to 3
Accounting Standards Update 2019-12 [Member]
ASU No 2019-12
Description of the business.
Description Of Business [Table]
Description Of Business [Table]
Document Period End Date
Document Period End Date
Series C Preferred Stock [Member]
Series C Convertible Preferred Stock
Income Statement Location [Axis]
Income Statement Location
Investments [Domain]
Accrued Liabilities, Current
Accrued liabilities
Total accrued liabilities
Fair value, assets, level 3 to level 2 transfers, amount.
Fair Value Assets Level3 To Level2 Transfers Amount
Transfer between level 3 to 2
Temporary equity issued period.
Temporary Equity Issued Period
Issue Period
Loss Contingencies [Table]
Loss Contingencies [Table]
Deferred Tax Liabilities Fixed Assets
Deferred Tax Liabilities Fixed Assets
Fixed assets
Common Stock, Shares Authorized
Common stock, shares authorized
Accrued Rent, Current
Deferred rent - short-term
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Lease liabilities - short-term
Operating Lease, Liability, Current
Accretion (Amortization) of Discounts and Premiums, Investments
Amortization of discount on investments, net
Class of Stock [Axis]
Class of Stock
Research and Development Expense (Excluding Acquired in Process Cost)
Research and development
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Anti dilutive securities excluded from computation of net loss per share
Cumulative Effect, Period of Adoption [Axis]
Gain (Loss) on Disposition of Assets
Loss on fixed asset disposals
Gain (Loss) on Disposition of Assets, Total
Deferred Tax Liabilities, Net [Abstract]
Deferred tax liabilities:
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of Assets Measured at Fair Value on Recurring Basis
Deferred Tax Assets, Net [Abstract]
Deferred tax assets:
Entity Address, Address Line Two
Entity Address, Address Line Two
Current Fiscal Year End Date
Current Fiscal Year End Date
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net (decrease) increase in cash and cash equivalents
Portion at Fair Value Measurement [Member]
Fair Value Disclosure Item Amounts [Default]
Portion at Fair Value Measurement [Member] [Default]
Operating Lease, Cost
Operating Lease, Cost
License Agreements [Table]
License agreements.
License Agreements [Table]
San Diego California
San Diego California [Member]
San Diego, California
Series C and D preferred stock.
Series C And D Preferred Stock [Member]
Series C and D Convertible Preferred Stock
Counterparty Name [Axis]
Assets [Abstract]
Assets
Income Tax Authority, Name [Domain]
Deferred Compensation Arrangement with Individual, Maximum Contractual Term
Options granted, maximum contractual term
Share based compensation arrangement by share based payment award minimum percentage of combined voting rights of common stock holders.
Share Based Compensation Arrangement By Share Based Payment Award Minimum Percentage Of Combined Voting Rights Of Common Stock Holders
Minimum percentage required for holders of combined voting power to be eligible for incentive stock options
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion to Common Stock (in shares)
Estimate of Fair Value Measurement [Member]
Fair Value
2022
Lessee, Operating Lease, Liability, to be Paid, Year One
Fair Value, Assets, Level 2 to Level 1 Transfers, Amount
Transfer between level 2 to 1
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Private Placement [Member]
Private Placement
Common Stock, Par or Stated Value Per Share
Common stock, par value
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Schedule of Provision for Income Taxes and Income Taxes Computed
Investments, Debt and Equity Securities [Abstract]
Additional Paid in Capital, Common Stock
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Research and Development Expense, Policy [Policy Text Block]
Research and Development Expenses and Accrued Research and Development Expenses
Document Type
Document Type
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Investments, Available-for-Sale
Preferred Stock, Value, Issued
Preferred stock, $0.0001 par value; 200,000,000 shares and no shares authorized at December 31, 2020 and December 31, 2019, respectively; no shares issued and outstanding at December 31, 2020 and December 31, 2019, respectively
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
Lessor, Leases [Policy Text Block]
Leases
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Liabilities
Assets, Current
Total current assets
Accounting Standards Update 2016-13 [Member]
ASU No. 2016-13
Share-based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Maximum number of additional common stock capital shares reserved for future issuance.
Maximum Number Of Additional Common Stock Capital Shares Reserved For Future Issuance
Additional number of shares available for future issuance
Share-based Payment Arrangement, Option [Member]
Stock Options
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term (in years), Options outstanding
Proceeds from Sale and Maturity of Marketable Securities
Sales and maturities of investments
Proceeds from Sale and Maturity of Marketable Securities, Total
Income Tax Expense (Benefit)
Provisions for income taxes
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing and financing activities:
Earnings Per Share, Basic and Diluted
Net loss per share, basic and diluted
Net loss per share, basic and diluted
Earnings Per Share, Basic and Diluted, Total
Antidilutive Securities [Axis]
Antidilutive Securities
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Measurement Basis [Axis]
Measurement Basis
Interest Income (Expense), Nonoperating, Net
Interest income, net
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforward
Deferred Tax Assets, Operating Loss Carryforwards, Total
Common Stock, Shares, Outstanding
Ending Balance (in shares)
Beginning Balance (in shares)
Common stock, shares, outstanding
Plan Name [Axis]
Plan Name
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Cumulative change in ownership period.
Cumulative Change In Ownership Period
Cumulative change in ownership period
Temporary equity stock issuance costs.
Temporary Equity Stock Issuance Costs
Preferred stock, issuance costs
Sale of Stock, Consideration Received on Transaction
Sale of Stock, Consideration Received on Transaction
Threshold Percentage of Value Decline in Equity Securities to be considered Other than Temporary Impairment
Cumulative change in ownership percentage
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents
Operating Expenses
Total operating expenses
IPO [Member]
Initial Public Offering
Financial Instruments [Domain]
Financial Instruments
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Issuance costs associated with offering of common stock
Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax
Unrealized Losses
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Exercise Price, Options outstanding Ending Balance
Weighted Average Exercise Price, Options outstanding Beginning Balance
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows from operating activities:
Research and Development in Process
Acquired in-process research and development
Underwriting discounts, commissions and other offering expenses.
Underwriting Discounts Commissions And Other Offering Expenses
Underwriting discounts and commissions and other offering expenses
Summary of Future Lease Payments of Operating Lease Liabilities
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Amount
Other permanent items
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Amount, Total
Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax
Unrealized Gains
Earnings Per Share [Abstract]
Debt Securities, Available-for-sale, Unrealized Loss Position, Number of Positions
Number of securities in unrealized loss position
Commercial milestone.
Commercial Milestone [Member]
Commercial Milestone
2023
Lessee, Operating Lease, Liability, to be Paid, Year Two
Basis of presentation and summary of significant accounting policies.
Basis Of Presentation And Summary Of Significant Accounting Policies [Line Items]
Basis Of Presentation And Summary Of Significant Accounting Policies [Line Items]
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Accrued Liabilities
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk
Scenario Two
Scenario Two [Member]
Not expire
Operating Lease, Weighted Average Discount Rate, Percent
Operating Lease, Weighted Average Discount Rate, Percent
Research and Development Expense [Member]
Research and development
Document Fiscal Period Focus
Document Fiscal Period Focus
Temporary Equity, Stock Issued During Period, Value, New Issues
Issuance of Series C and D preferred stock, net of issuance costs of $135
Accounting Policies [Abstract]
Computer hardware and software.
Computer Hardware And Software [Member]
Computer Hardware and Software
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Two thousand fourteen equity incentive plan.
Two Thousand Fourteen Equity Incentive Plan [Member]
2014 Plan
Entity Address, Address Line One
Entity Address, Address Line One
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value
Intrinsic value of options exercised
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number
Options outstanding, Ending Balance
Options outstanding, Beginning Balance
Liabilities, Current
Total current liabilities
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate, maximum
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate Intrinsic Value, Options outstanding
Total minimum lease payments
Lessee, Operating Lease, Liability, to be Paid
Temporary Equity, Carrying Amount, Attributable to Parent
Ending Balance
Beginning Balance
Convertible preferred stock, $0.0001 par value; no shares and 20,348,788 shares authorized at December 31, 2020 and December 31, 2019, respectively; no shares and 19,278,606 issued and outstanding at December 31, 2020 and December 31, 2019, respectively; aggregate liquidation preference of $0 and $178,058 at December 31, 2020 and December 31, 2019, respectively
Federal return to provision
Income Tax Reconciliation Federal Return to Provision
Income tax reconciliation federal return to provision.
Lease liability
Deferred Tax Asset Lease liability
Deferred tax asset lease liability
Proceeds from Issuance Initial Public Offering
Proceeds from issuance of common stock pursuant to initial public offering
Convertible Preferred Stock [Member]
Convertible Preferred Stock
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State tax
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Equity Components [Axis]
Equity Components
Assets, Current [Abstract]
Current assets:
Entity Registrant Name
Entity Registrant Name
Series A Preferred Stock [Member]
Series A Convertible Preferred Stock
Entity Interactive Data Current
Entity Interactive Data Current
Entity Address, City or Town
Entity Address, City or Town
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, minimum
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Trading Symbol
Trading Symbol
Long Term Investments [Member]
Long Term Investments [Member]
Long Term Investments
Net Cash Provided by (Used in) Investing Activities [Abstract]
Cash flows from investing activities:
Less: interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Short-term Investments [Member]
Short-term Investments
Local Phone Number
Local Phone Number
Accounting Standards Update 2016-02 [Member]
ASC 842
Share Based Compensation Arrangement By Share Based Payment Award Shares Issued Subject To Repurchase Liabilities Recorded
Liabilities with shares issued with repurchase rights
Share based compensation arrangement by share based payment award shares issued subject to repurchase liabilities recorded.
Total stockholders' equity
Stockholders' Equity Attributable to Parent
Ending Balance
Beginning Balance
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Other
Accruals and other
Unrecognized Tax Benefits
Unrecognized tax benefits
Unrecognized Tax Benefits, Beginning Balance
Unrecognized Tax Benefits, Ending Balance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Change in valuation allowance
Operating Lease, Payments
Operating Lease, Payments
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Preferred Stock, Shares Issued
Preferred stock, shares, issued
Preferred Stock, Shares Issued, Total
Assets, Fair Value Disclosure
Assets, Fair Value
Statistical Measurement [Axis]
Statistical Measurement
Entity Small Business
Entity Small Business
Preferred Stock, Shares Outstanding
Preferred stock, shares, outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period
Options, Forfeited and cancelled
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Total
Share Price
Price per share of common stock
Stock price
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
APIC, Share-based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Over-Allotment Option [Member]
Option to Purchase Additional Shares
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Significant Components of Deferred Tax Assets and Liabilities
Accrued Liabilities, Current [Abstract]
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Property and Equipment
Research tax credit carryforward
Research Tax Credit Carryforward [Member]
Property, Plant and Equipment, Useful Life
Estimated useful lives of related assets
Share based compensation arrangement by share based payment award options not be granted at less than fair market value of common stock at date of grant maximum term.
Share Based Compensation Arrangement By Share Based Payment Award Options Not Be Granted At Less Than Fair Market Value Of Common Stock At Date Of Grant Maximum Term
Maximum term of options may not be granted at less than fair market value of the common stock at the date of grant
Operating Leases, Future Minimum Payments Due
Total minimum lease payments
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Deferred Rent
Deferred rent
Balance Sheet Location [Axis]
Balance Sheet Location
License agreement maximum milestone payment obligation to pay.
License Agreement Maximum Milestone Payment Obligation To Pay
License agreement maximum milestone payment obligation to pay
Net Income (Loss) Attributable to Parent [Abstract]
Numerator
Deferred Charges, Policy [Policy Text Block]
Deferred Offering Costs
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Granted
Sale of Stock [Domain]
Sale of Stock
Basis of presentation and summary of significant accounting policies.
Basis Of Presentation And Summary Of Significant Accounting Policies [Table]
Basis Of Presentation And Summary Of Significant Accounting Policies [Table]
Temporary Equity, Shares Issued
Convertible preferred stock, issued
Shares Issued
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Plan Name [Domain]
Plan Name
Contingent Consideration Type [Domain]
Contingent Consideration Type
Temporary Equity, by Class of Stock [Table]
Temporary Equity By Class Of Stock [Table]
Operating Leases, Future Minimum Payments Due, Next Twelve Months
2021
Depreciation
Depreciation
Depreciation expense
Depreciation, Total
Defined Contribution Plan, Cost
Defined Contribution Plan, Cost
Operating Loss Carryforwards, Expiration Date
Operating loss carryforwards, expiration
Lessee, Operating Lease, Term of Contract
Operating lease, term of contract
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increase in valuation allowance
Shares issued percentage of premium.
Shares Issued Percentage Of Premium
Premium percentage
Stock Issued During Period, Value, New Issues
Offering of common stock
Accrued Liabilities, Total
Accrued Liabilities
Accrued Liabilities
Proceeds from issuance initial public offering, net of issuance cost.
Proceeds From Issuance Initial Public Offering Net Of Issuance Cost
Net proceeds from IPO
CALIFORNIA
CALIFORNIA
Debt Securities, Available-for-sale, Noncurrent
Investments, available-for-sale
Right of use assets
Deferred Tax Liabilities Right of Use Assets
Deferred tax liabilities right of use assets
Share-based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Preferred Stock, Dividend Rate, Per-Dollar-Amount
Dividend Annual Rate per Share
Number of licensed products obliged to develop and commercialize.
Number Of Licensed Products Obliged To Develop And Commercialize
Number of licensed products obliged to develop and commercialize
Share-based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Option Activity
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Fair value, assets, level 3 to level 1 transfers, amount
Fair Value Assets Level3 To Level1 Transfers Amount
Transfer between level 3 to 1
Temporary Equity [Table Text Block]
Schedule of Convertible Preferred Stock Authorized and Issued and its Principal Terms
Proceeds from Issuance of Preferred Stock and Preference Stock
Proceeds from issuance of preferred stock, net of issuance costs
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number
Options, Exercisable
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Commitments and Contingencies Disclosure [Abstract]
Temporary equity stock issued during period shares net of issuance costs.
Temporary Equity Stock Issued During Period Shares Net Of Issuance Costs
Issuance of Series C and D preferred stock, net of issuance costs of $135 (in shares)
Assets
Total assets
Fair Value, Inputs, Level 2 [Member]
Level 2
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period
Exercise of common stock options (in shares)
Options, Exercised
Statement [Line Items]
Statement [Line Items]
Total liabilities and stockholders' equity
Liabilities and Equity
Balance Sheet Location [Domain]
Balance Sheet Location
Property, Plant and Equipment [Abstract]
Statement of Cash Flows [Abstract]
Additional Paid-in Capital [Member]
Additional Paid-in Capital
Income Tax Examination, Penalties and Interest Accrued
Accrual for interest or penalties
Income Tax Examination, Penalties and Interest Accrued, Total
Title of 12(b) Security
Title of 12(b) Security
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Comprehensive loss
Two thousand and twenty employee stock purchase plan.
Two Thousand And Twenty Employee Stock Purchase Plan [Member]
2020 ESPP
Proceeds from issuance of common stock gross.
Proceeds From Issuance Of Common Stock Gross
Gross proceeds from secondary public offering excluding underwriting discounts and commissions and other offering expenses
Fair Value, Inputs, Level 3 [Member]
Level 3
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Two thousand twenty equity incentive plan and two thousand fourteen equity incentive plan.
Two Thousand Twenty Equity Incentive Plan And Two Thousand Fourteen Equity Incentive Plan [Member]
2020 Plan and 2014 Plan
Voronoi Inc.
Voronoi Inc [Member]
Voronoi Inc.
Award Type
Award Type [Domain]
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period
Expiration period
Federal
Federal [Member]
Federal.
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Accounts payable and accrued other liabilities
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment, Net
Fair Value, Inputs, Level 1 [Member]
Level 1
License agreements disclosure.
License Agreements Disclosure [Text Block]
License Agreements
2025
Lessee, Operating Lease, Liability, to be Paid, Year Four
Deferred income taxes, net
Deferred Tax Assets, Net
Nonoperating Income (Expense)
Total other income
Fair Value, by Balance Sheet Grouping [Table]
Fair Value By Balance Sheet Grouping [Table]
Total deferred tax liabilities
Deferred Tax Liabilities, Net
Temporary Equity, Liquidation Preference
Aggregate liquidation preference
Aggregate Liquidation Preference
Acquired in-process research and development expense.
Acquired In Process Research And Development Expense [Member]
Acquired In-Process Research and Development Expense
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross
Options, Granted
Entity Current Reporting Status
Entity Current Reporting Status
Investment Type [Axis]
Entity Voluntary Filers
Entity Voluntary Filers
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate, minimum
Scenario [Domain]
Scenario
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Money Market Funds [Member]
Money Market Funds
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Lessee, Operating Lease, Option to Extend
Extend the lease term
Debt Securities, Available-for-sale [Table]
Debt Securities Available For Sale [Table]
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Share
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Total Stock-based Compensation Expense
Retirement Benefits [Abstract]
Operating Leases, Future Minimum Payments, Due in Two Years
2022
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Loss
Auditor Firm ID
Accrued clinical and manufacturing costs.
Accrued Clinical And Manufacturing Costs
Accrued clinical and manufacturing costs
Income Statement Location [Domain]
Income Statement Location
Auditor Name
Cumulative Effect, Period of Adoption, Adjustment [Member]
Cumulative Effect, Period of Adoption, Adjustment
Fair Value, assets, level 2 to level 3 transfers, amount.
Fair Value Assets Level2 To Level3 Transfers Amount
Transfer between level 2 to 3
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted Average Exercise Price, Exercisable
License agreement shares issued value related to acquired assets charge.
License Agreement Shares Issued Value Related To Acquired Assets Charge
License agreement shares issued value related to acquired assets charge
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Interest and penalties not recognized
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Minimum [Member]
Minimum
Temporary equity conversion to common stock value.
Temporary Equity Conversion To Common Stock Value
Conversion to Common Stock
Incentive stock options.
Incentive Stock Options [Member]
Incentive Stock Options
Measurement Frequency [Domain]
Measurement Frequency
Stock Issued During Period, Value, Stock Options Exercised
Exercise of common stock options
Other Noncurrent Assets [Member]
Other Assets
Document Annual Report
Document Annual Report
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Less valuation allowance
Deferred Tax Assets, Valuation Allowance, Total
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities:
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Total unrecognized compensation expense related to outstanding unvested stock-based awards
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Share-based compensation arrangement by share-based payment award number of shares subject to repurchase.
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Subject To Repurchase
Shares subject to repurchase
Scenario One
Scenario One [Member]
Begin to expire in 2034
Unpaid deferred financing costs.
Unpaid Deferred Financing Costs
Unpaid deferred financing costs
Entity Filer Category
Entity Filer Category
Income Tax, Policy [Policy Text Block]
Income Taxes
Document Fiscal Year Focus
Document Fiscal Year Focus
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-average grant-date fair value of options granted
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Adjustment to opening balance of accumulated deficit
Income Tax Disclosure [Text Block]
Income Tax
Entity Ex Transition Period
Entity Ex Transition Period
Convertible preferred stock.
Convertible Preferred Stock Disclosure [Text Block]
Convertible Preferred Stock
Fair Value Disclosures [Abstract]
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, Net
Deferred Costs, Noncurrent
Deferred offering costs
Deferred Costs, Noncurrent, Total
Maximum
Maximum [Member]
Entity Central Index Key
Entity Central Index Key
Options to purchase common stock.
Options To Purchase Common Stock [Member]
Options to Purchase Common Stock
Cash, Cash Equivalents and Restricted Cash
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Rent expense
Operating Lease, Expense
Temporary Equity [Line Items]
Temporary Equity [Line Items]
Stock Issued During Period, Value, Acquisitions
Issuance of common stock related to acquired-in- process research and development
Statutory rate
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Temporary Equity Disclosure [Abstract]
Entity Tax Identification Number
Entity Tax Identification Number
Equity Component [Domain]
Equity Component
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Debt Securities, Available-for-sale [Table Text Block]
Schedule of Cost, Gross Unrealized Holding Gains, Gross Unrealized Holding Losses and Fair Value of Available for Sale Investments
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Stockholders' Equity Note, Stock Split, Conversion Ratio
Reverse stock split ratio
License agreement charge related to acquired assets.
License Agreement Charge Related To Acquired Assets
License agreement charge related to acquired assets
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Total unrecognized compensation expense related to outstanding unvested stock-based awards expected to be recognized over weighted-average remaining service period
Upfront cash payment.
Upfront Cash Payment
Upfront cash payment
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in accounting principle, accounting standards update, adoption date
Leasehold Improvements [Member]
Leasehold Improvements
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized
Number of common stock initially reserved for issuance
License agreement additional Milestone payment.
License Agreement Additional Milestone Payment
License agreement, additional milestone payment
Statement [Table]
Statement [Table]
Operating Lease, Weighted Average Remaining Lease Term
Operating Lease, Weighted Average Remaining Lease Term
Entity File Number
Entity File Number
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock transfer restrictions period.
Stock Transfer Restrictions Period
Stock transfer restrictions period
Retained Earnings [Member]
Accumulated Deficit
Shares Issued, Price Per Share
Issue Price per Share
Issue price per share
Accounting Standards Update [Domain]
Accounting Standards Update
Accounting Standards Update [Axis]
Accounting Standards Update
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Basis of Presentation and Significant Accounting Policies [Text Block]
Basis of Presentation and Summary of Significant Accounting Policies
Liabilities, Current [Abstract]
Current liabilities:
Share-based Payment Arrangement [Text Block]
Equity Incentive Plans and Stock-Based Compensation
Lab equipment.
Lab Equipment [Member]
Lab Equipment
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Present value of lease liabilities
Operating Lease, Liability, Total
Operating Lease, Liability
Lease liabilities
Common Stock [Member]
Common Stock
Property, Plant and Equipment, Gross
Total property and equipment, gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Entity Public Float
Entity Public Float
Restricted Cash and Cash Equivalents, Total
Restricted Cash and Cash Equivalents
Restricted cash included in other assets
Cover [Abstract]
Research and development credits
Deferred Tax Assets, Tax Credit Carryforwards, Research
Temporary Equity, Shares Outstanding
Ending Balance (in shares)
Beginning Balance (in shares)
Convertible preferred stock, outstanding
Shares Outstanding
Statement of Stockholders' Equity [Abstract]
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Number of Operating Segments
Number of operating segments
Share-based Payment Arrangement [Abstract]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-based Payment Arrangement, Amount
Stock-based compensation
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value of Financial Instruments
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Other Accrued Liabilities, Current
Other accruals
Document Transition Report
Document Transition Report
Proceeds from Stock Options Exercised
Proceeds from stock option exercises
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Forfeited and Cancelled
Public offering.
Public Offering [Member]
Public Offering
Operating lease, renewal term
Lessee, Operating Lease, Renewal Term
Stock Issued During Period, Shares, Acquisitions
Issuance of common stock related to acquired-in-process research and development (in shares)
Share-based Payment Arrangement, Expense
Stock-based compensation expense
Statement of Financial Position [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible
At-The-Market Sales Agreement and Offering [Member]
At-The-Market Sales Agreement and Offering.
At The Market Sales Agreement And Offering Member
Series D Preferred Stock [Member]
Series D Convertible Preferred Stock
Description of the Business.
Description Of Business [Line Items]
Description Of Business [Line Items]
2026
Lessee, Operating Lease, Liability, to be Paid, Year Five
Deferred rent policy.
Deferred Rent Policy Policy [Text Block]
Deferred Rent
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders' equity (deficit):
Conversion of Stock, Shares Converted
Convertible preferred stock outstanding converted into shares of common stock
Nature of Operations [Text Block]
Description of the Business
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents
Payments to Acquire Investments
Purchases of investments
Payments to Acquire Investments, Total
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Summary of Computation of Basic and Diluted Net Loss Per Share
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Exercised
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
2024
Lessee, Operating Lease, Liability, to be Paid, Year Three
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Common Stock, Capital Shares Reserved for Future Issuance
Number of shares available for future issuance
Measurement Frequency [Axis]
Measurement Frequency
Award Type [Axis]
Award Type
Entity Shell Company
Entity Shell Company
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Other comprehensive loss:
Sale of Stock, Price Per Share
Sale of stock, price per share
New Accounting Pronouncements Not Yet Adopted [Policy Text Block]
New Accounting Pronouncements Not Yet Adopted Policy [Text Block]
New Accounting Pronouncements Not Yet Adopted
Debt Securities, Available-for-sale [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Liabilities and Equity [Abstract]
Liabilities, Convertible Preferred Stock and Stockholders' Equity (Deficit)
Retirement Benefits [Text Block]
Employee Benefit Plan
Number of period the agreement in effect.
Number Of Period Agreement In Effect
Number of period the agreement in effect
Income Tax Authority, Name [Axis]
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Payments Of Stock Issuance Costs Associated With Financings
Payments Of Stock Issuance Costs Associated With Financings
Issuance costs associated with financings
Issuance costs associated with financings
Counterparty Name [Domain]
Fair Value Measurement [Domain]
Fair Value Measurement
Development and regulatory milestone.
Development And Regulatory Milestone [Member]
Development And Regulatory Milestone
Non-cash stock consideration, acquisition.
Non Cash Stock Consideration Acquisition
Non-cash stock consideration, acquisition
Amendment Flag
Amendment Flag
Conversion of Stock, Amount Converted
Conversion of preferred stock to common stock
Sale of Stock, Number of Shares Issued in Transaction
Sale of stock, number of shares issued in transaction
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Other Nonoperating Income
Other income
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted Accounting Pronouncements
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Tax credit carryforward
Tax Credit Carryforward, Amount
Long-term Debt, Total
Long-term Debt
Long-term Debt
Fair Value, Recurring [Member]
Fair Value Measurements Recurring
Secondary public offering.
Secondary Public Offering [Member]
Secondary Public Offering
South San Francisco, California.
South San Francisco California [Member]
South San Francisco, California
Fair Value, Assets, Level 1 to Level 2 Transfers, Amount
Transfer between level 1 to 2
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Other Assets, Noncurrent
Other assets
Other Assets, Noncurrent, Total
Employee Stock [Member]
Employee Stock Purchase Plan
Geographical [Domain]
Geographical
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate Intrinsic Value, Exercisable
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent
Exercise price as a percentage of fair market value
Sale of Stock [Axis]
Sale of Stock
Fair Value Disclosures [Text Block]
Fair Value Measurements
Cumulative Effect, Period of Adoption [Domain]
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock