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                          December 22, 2023

       Dominic Piscitelli
       Chief Financial Officer
       Oric Pharmaceuticals, Inc.
       240 E. Grand Ave, 2nd Floor
       South San Francisco, CA 94080

                                                        Re: Oric
Pharmaceuticals, Inc.
                                                            Registration
Statement on Form S-3
                                                            Filed December 15,
2023
                                                            File No. 333-276077

       Dear Dominic Piscitelli:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Lauren
Hamill at 303-844-1008 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Life Sciences
       cc:                                              Amanda Urquiza